Nobody likes painful sensations - they cause severe discomfort; because of pain, a person cannot lead a normal lifestyle and fully enjoy it. Fortunately, coping with pain syndrome today is quite simple - pharmacies offer a large selection of painkillers that help not only alleviate the condition, but also prevent the recurrence of unpleasant painful sensations.
It is quite difficult to understand the huge range of these drugs: they differ from each other in their principle of action, the active substance used, existing contraindications and possible side effects. The main thing to remember when buying painkillers is that they must be prescribed by your doctor. It is not advisable to purchase such drugs without his recommendation. Our rating of the best painkillers presents the most popular remedies among patients. First of all, when compiling this review, we relied on user reviews, as well as the price-quality ratio of the product.
Which painkiller is best to buy?
Having familiarized yourself with the types of painkillers, you can easily select the one that will quickly eliminate the pain symptom:
Analgesics - drugs based on analgin, metamizole and paracetamol are effective against headaches and toothaches, and some of them provide an additional antipyretic effect.
Remember that analgesics do not affect the cause of the disease, only temporarily relieving a pain attack, but they form an addiction.
Nonsteroidal anti-inflammatory drugs are a group of medications based on diclofenac, ibuprofen and nimesulide with a pronounced analgesic and anti-inflammatory effect. NSAIDs are effective for neuralgia, joint pain, gastroenterological pain, postoperative and menstrual pain, renal colic and more. Moreover, if analgesics only mask pain, NSAIDs, due to their anti-inflammatory effect, prevent further development of the disease.
Drugs with an antipyretic effect are a group of combined painkillers used for feverish conditions, made from paracetamol and ibuprofen. Such medications are effective for influenza, acute respiratory infections and other infectious and inflammatory diseases. But do not take fever-reducing medications for more than 3 days in a row without your doctor's approval.
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What kind of pain is there?
Doctors divide pain into two main categories: acute and chronic.
Acute pain is not long-lasting, it occurs suddenly, usually due to easily diagnosed causes (for example, a burn of a finger, a broken bone, etc.).
Chronic pain – persists for a long period of time (months, years). It accompanies many diseases, such as rheumatism, cancer, osteoarthritis, etc.
Taking painkillers can blur or even completely hide the symptoms of a serious illness. For example, in case of acute pain in the abdomen or heart, you should never take painkillers - this is fraught with untimely or incorrect diagnosis, which can lead to dire consequences. Therefore, before taking the drug, it is imperative to consult your doctor.
The best analgesics
Such drugs reduce the perception of pain impulses, resulting in short-term relief of the condition. Taking analgesics is advisable for headaches associated with meteosensitivity and hangover syndrome. They also relieve toothache before going to the doctor. Do not use them for a long time, because they do not solve the existing health problem, but have a toxic effect on the body.
Akrikhin "Nolodatak"
5
★★★★★
editorial assessment
100%
buyers recommend this product
A non-opioid analgesic of central action in capsule form has a pronounced analgesic and muscle relaxant effect. The drug contains 100 mg of flupirtine. The drug is effective against mild and moderate pain attacks, and the effect of taking it occurs within 30 minutes.
Nolodatac is taken 1 capsule up to 4 times a day, the duration of therapy should not exceed more than 2 weeks. Increasing dosages can lead to loss of appetite, skin rashes, anxiety, dizziness, diarrhea and sweating.
The drug is contraindicated in minors, in the presence of alcoholism, renal and liver failure. Due to insufficient clinical data on safety, Nolodatac is not prescribed to pregnant and lactating women.
Advantages:
- Universal remedy;
- Quickly relieves pain;
- Long-term use is possible;
- Minimal contraindications;
- No adverse reactions if instructions are followed.
Flaws:
- Contraindicated for children.
Nolodatac is a savior from all types of pain that can be taken for a long time. By putting it in your first aid kit, you can easily get rid of sudden dental, joint and other types of pain.
Upsa SAS "Efferalgan"
4.9
★★★★★
editorial assessment
95%
buyers recommend this product
Paracetamol in the form of effervescent tablets will quickly eliminate pain from injuries, burns, bruises, myalgia and relieve fever from acute respiratory infections. The drug is approved for use from 12 years of age in a dosage of 1-2 tablets up to 3 times a day. The duration of treatment should not exceed 5 days. If the instructions are not followed, allergic reactions, bronchospasms, dizziness and nausea are possible.
Efferalgan is contraindicated in cases of viral hepatitis, renal and liver failure, and alcoholism. It is also used with caution in old age. The drug can be prescribed during periods of lactation and pregnancy for a course of no more than 3 days.
Advantages:
- Convenient release form;
- Can be taken during pregnancy and lactation;
- Versatility;
- Pronounced analgesic effect;
- Affordable price (up to 200 rubles).
Flaws:
- There is no anti-inflammatory effect.
Efferalgan is a universal drug for all types of pain. Its use is recommended in the complex therapy of influenza, acute respiratory infections and other febrile conditions.
Biochemist "Migrenium"
4.9
★★★★★
editorial assessment
90%
buyers recommend this product
The combination of paracetamol and caffeine in tablet form is effective against muscle pain, headaches and toothaches, and can also be used in combination therapy for influenza. The drug is taken 2 tablets 4 times a day for no more than 10 days. Increasing doses is fraught with allergic reactions, anemia and nausea.
Migraine is prohibited for use by children under 12 years of age, with epilepsy, insomnia, arterial hypertension, renal and liver failure. There is no data on the teratogenicity of this complex, so do not use it during pregnancy and lactation.
Advantages:
- Helps with many types of pain;
- Allowed for admission from 12 years of age;
- Minimum restrictions;
- Quick effect;
- Affordable price (about 150 rubles).
Flaws:
- Adverse reactions are possible.
Migraine is recommended for people suffering from regular neurological headaches.
Analgin Avexima
4.8
★★★★★
editorial assessment
89%
buyers recommend this product
An analgesic-antipyretic based on metamizole sodium is used for pain in adults and children over 2 years of age. The drug in tablet form is prescribed for migraines, colic, minor burns and injuries. The drug is taken up to 3 times a day for no more than 5 days in a row without consulting a doctor.
Possible adverse reactions: Quincke's edema, skin rash, leukopenia. Analgin Avexima is contraindicated in the first trimester of pregnancy, as well as in cases of serious impairment of liver and kidney function. Taking this drug together with NSAIDs increases the toxic effect of treatment.
Advantages:
- Versatility;
- Long-term use is possible;
- Relieves the condition for up to 6 hours;
- Suitable for children from 2 years old;
- Can be taken in the second and third trimesters of pregnancy;
- Affordable price (about 65 rubles).
Flaws:
- Ineffective in combating severe pain.
Analgin Avexima is a universal drug in the fight against moderate pain, suitable for women in the second and third trimesters of pregnancy.
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Antispasmodics
Antispasmodics eliminate attacks of spastic pain that arise from various diseases of the internal organs. The antispasmodic effect is achieved by acting directly on smooth muscle cells or by blocking the transmission of nerve impulses.
Advantages
The drugs help reduce pain in diseases of the digestive system, biliary tract, kidneys and bladder, and pelvic organs. Effectively eliminate colic and pain due to irritable bowel syndrome. With caution, under medical supervision, drugs can be prescribed to pregnant and lactating women and children.
Flaws
The drugs have a fairly wide list of contraindications, including tuberculosis, severe forms of renal, liver and heart failure, and some types of colitis.
The best non-steroidal anti-inflammatory painkillers
Such drugs block pain and have an anti-inflammatory effect, easing the condition of joint diseases and neuralgia. Typically, over-the-counter vasodilators stimulate tissue healing and are suitable for a course of treatment. However, NSAIDs often cause side effects such as nausea and weakness, so do not increase the recommended daily dose of the medication.
Otisfarm "Next Uno Express"
4.9
★★★★★
editorial assessment
95%
buyers recommend this product
With these ibuprofen-based capsules, you will forget about any pain after a few minutes. The drug is prescribed to adults and children over 12 years of age, one capsule up to 4 times a day. Its particular effectiveness is noted in the fight against migraines, neuralgia, rheumatism, dental and menstrual pain. Taking the drug for more than 5 days in a row at maximum dosages often provokes dizziness, nausea, weakness, hypotension, and disturbances in the gastrointestinal tract.
Next Uno Express has many positive reviews due to its rapid pain relief effect that lasts up to 8 hours. The main contraindications to the drug include pregnancy, lactation, kidney and liver diseases, heart failure and bleeding disorders.
Advantages:
- Express effect;
- Helps with all types of pain;
- Allowed for admission from 12 years of age;
- Long lasting;
- Does not provoke adverse reactions when taken occasionally.
Flaws:
- Not recommended for long-term use.
Next Uno Express is especially recommended for intercostal neuralgia, because it quickly relieves pain and helps you breathe deeply.
JSC MPA "Dialrapid"
4.9
★★★★★
editorial assessment
91%
buyers recommend this product
The painkiller in powder form contains 50 mg of diclofenac. The main indications for its use are post-traumatic and post-operative pain, inflammation, migraine, neuralgia, myalgia and joint pain. The drug is prescribed from the age of 14 in an amount of up to 4 sachets per day.
Exceeding dosages provokes drowsiness, weakness, hearing impairment, negative reactions from the cardiovascular system and digestion. Diapralide can be used in the first and second trimesters of pregnancy if the benefits of the drug outweigh the possible risks to the fetus.
Advantages:
- Helps with severe pain;
- In emergency situations, it can be prescribed to pregnant women;
- Antipyretic and anti-inflammatory effect;
- Effect within 30 minutes;
- Versatile.
Flaws:
- Provokes serious adverse reactions when the dose is exceeded.
Dialrapid is recommended for eliminating acute pain attacks due to domestic injuries and the inability to seek medical help.
JSC Obolenskoe "Dexonal"
4.9
★★★★★
editorial assessment
90%
buyers recommend this product
A non-steroidal anti-inflammatory drug based on dexketoprofen has a pronounced analgesic and restorative effect. The drug is taken with food no more than 3 times a day for musculoskeletal and dental pain, as well as for algodismenorrhea. The course of treatment is no more than 5 days.
The analgesic effect is achieved after 20 minutes. Increasing dosages threatens migraines, weakness, allergies, insomnia and visual impairment. Taking Dexonal is prohibited for ulcers, bronchial asthma, liver disease, kidney disease, heart failure, and is also not recommended for minors, pregnant and lactating women.
Advantages:
- Fast analgesic effect;
- Anti-inflammatory effect;
- Wide range of applications;
- The effect lasts up to 8 hours;
- Affordable price (about 220 rubles).
Flaws:
- Exceeding recommended doses is unacceptable.
Dexonal is not suitable for long-term treatment, but due to its pronounced and rapid analgesic effect, this drug will be appreciated by women suffering from menstrual pain.
Bayer "Aspirin Express"
4.8
★★★★★
editorial assessment
88%
buyers recommend this product
Effervescent tablets containing 500 mg of acetylsalicylic acid will eliminate headaches in 15 minutes. A drug with analgesic, anti-inflammatory and antipyretic effects is prescribed from the age of 15 in the absence of diseases of the gastrointestinal tract, kidneys and liver. The drug is prohibited for use by pregnant and lactating women.
To combat migraines, dissolve 2 effervescent tablets (1 g) in a glass of water. The maximum daily dosage is 3 grams. Failure to follow the instructions may result in nausea, vomiting, dizziness and allergic reactions. Do not use Aspirin Express for more than 3 days in a row without consulting your doctor.
Advantages:
- Convenient release form;
- Express effect;
- Complex action;
- No adverse reactions if instructions are followed.
Flaws:
- There are contraindications.
Aspirin Express is recommended for occasional use for headaches by people suffering from weather sensitivity.
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The best combined action painkillers
An increase in body temperature is typical for influenza, acute respiratory infections, injuries, allergies, internal hemorrhages and cancerous tumors. Undoubtedly, in any of these cases it is important to consult a doctor in time, but the following combination drugs will help to temporarily alleviate the condition.
Reckitt Benckiser Healthcare International LTD "Nurofen Long"
5
★★★★★
editorial assessment
100%
buyers recommend this product
Tablets based on ibuprofen and paracetamol are approved for use from 2 years of age. The main indications for their use include pain and joint syndromes, bruises and inflammation of soft tissues, fever, neuralgia, dental and menstrual pain. The drug is taken 1 tablet up to three times a day and no more than 3 days. A pronounced analgesic and antipyretic effect as a result of its administration is achieved within 60 minutes and lasts up to 8 hours.
Nurofen Long is contraindicated for ulcers, gastrointestinal bleeding, in the third trimester of pregnancy and lactation. Using this medication with other NSAIDs provokes symptoms of overdose and increases their toxic effect on the body.
Advantages:
- Versatility;
- Complex action;
- Effect up to 8 hours;
- Can be prescribed to children;
- Allowed for use in the first and second trimesters of pregnancy.
Flaws:
- Combination with NSAIDs is undesirable.
Nurofen Long, thanks to its intense and long-lasting effect, will relieve severe pain in the postoperative period, and will also help with fractures, dislocations and severe bruises.
Safiston Atoll
4.9
★★★★★
editorial assessment
97%
buyers recommend this product
A highly effective remedy for headaches, dental and muscle pain in the form of tablets, intended for adults and children over 12 years of age. A combination of paracetamol, caffeine and propyphenazone is taken up to 3 tablets per day 1-2 hours after meals. The duration of such treatment should not exceed days.
The analgesic and antipyretic effect of taking the drug is achieved within an hour and lasts up to 6 hours. If doses are exceeded, dizziness, insomnia, skin rashes, vomiting and nausea are possible. The main contraindications to taking Safiston are diseases of the cardiovascular system, gastrointestinal tract, kidneys, liver, as well as periods of pregnancy and breastfeeding.
Advantages:
- Pronounced analgesic effect;
- Allowed for children;
- Long-term analgesic effect;
- Long-term use is possible without consultation with the doctor;
- Affordable price (about 150 rubles).
Flaws:
- There are many contraindications.
Safiston is a universal drug for acute pain attacks, which can be taken without fear even by teenagers - but taking into account all contraindications.
Marbiopharm "Citramarin"
4.9
★★★★★
editorial assessment
90%
buyers recommend this product
First aid for influenza, acute respiratory infections and other febrile conditions based on analgin, paracetamol and caffeine. The product in powder form is diluted in 100 ml of hot water. Frequency of administration – up to 3 times a day for no more than 5 days in a row. Failure to follow the instructions provokes vomiting, dizziness, weakness, blurred vision and bleeding gums.
Citramarin is contraindicated in pregnancy, lactation, hemophilia, hyperexcitability, renal failure, and in persons under 15 years of age. Due to its analgesic effect, the drug is also effective for neuralgia and algodismenorrhea.
Advantages:
- Pronounced antipyretic effect;
- Analgesic effect;
- Suitable for long-term use;
- Available in various flavors (orange, lemon);
- Affordable price - 200 rubles for 10 sachets.
Flaws:
- Contraindicated for children.
Citramarine is a budget antipyretic drug that will help reduce fever and relieve pain in severe bruises.
comparison table
In order to compare the presented products, we recommend taking a look at the table with their characteristics.
| Model | Routes of administration | Recipe | Active substance | Price, rub) |
| Ibuprofen tab. p/o 200 mg No. 20 | externally, orally, rectally, intravenously | available without a prescription | ibuprofen | from 19 to 25 |
| Diclofenac tab.prolong.p.p.o. 100 mg No. 20 | externally, orally, intravenously | available without a prescription | diclofenac | from 52 to 85 |
| Aertal por. d/prig. susp. d/in. taking 100 mg, pack. 3 g No. 20 | orally | prescription | aceclofenac | from 400 to 500 |
| Pentalgin tab. p/o captivity. No. 24 | orally | not needed | paracetamol, caffeine, naproxen, drotaverine hydrochloride and pheniramine maleate | from 210 to 290 |
| Nurofen forte tab. p.o 400 mg No. 12 | orally | not needed | ibuprofen | from 110 to 225 |
| Solpadeine Fast tab. sol. No. 12 | orally | not needed | paracetamol and caffeine | from 219 to 369 |
| Nurofen (from 6 years old) tab. p/o 200 mg No. 8 | orally | not needed | ibuprofen | from 209 to 407 |
| Analgin tablet. 500 mg No. 10 | inside | No | metamizole sodium | from 63 to 210 |
The best painkillers for children
Most serious painkillers are prohibited for the youngest patients due to the lack of clinical data on their safety and large dosages of the active substance. We will tell you about painkillers that are suitable for eliminating all types of pain in babies.
Dr. Reddy's "Ibuklin Junior"
5
★★★★★
editorial assessment
100%
buyers recommend this product
A combined painkiller for children over 2 years of age has a fruity aroma and a pronounced therapeutic effect.
The product contains a combination of paracetamol and ibuprofen, which is effective for any pain syndromes of moderate severity and febrile conditions. The drug is prescribed 1 tablet 3 times a day for no more than 3 days. The therapeutic effect of taking it is achieved within one hour.
Long-term treatment and excess doses are fraught with insomnia, diarrhea, nausea, swelling and skin rashes. Contraindications to children's Ibuklin include asthma, kidney and liver diseases, and stomach ulcers. The drug can also be prescribed to women in the second and third trimesters of pregnancy.
Advantages:
- Combined action;
- Minor contraindications;
- The tablets have a pleasant aroma;
- Relieves any pain in an hour;
- Affordable price (about 150 rubles).
Flaws:
- Not suitable for long-term use.
Ibuklin Junior is a highly effective pain reliever for injuries, bruises, sprains and fractures that are inevitable in little fidgets.
Otispharm "Maxicold" for children
4.9
★★★★★
editorial assessment
92%
buyers recommend this product
Sweet syrup with intense analgesic, anti-inflammatory and antipyretic effects is approved for use from 3 months. The drug contains ibuprofen, which is effective for joint pain, dental pain and headaches, as well as stomach colic, myalgia, gout and more. The drug is taken in dosages of 20-40 mg/1 kg of body weight up to 3 times a day for up to 3 weeks.
If the instructions are not followed, vomiting, skin rash, insomnia, hyperexcitability and other symptoms of overdose are possible. Maxicold is also contraindicated in cases of kidney and liver dysfunction. This syrup is available for sale in strawberry and orange flavors, each of which will appeal to the pickiest little ones.
Advantages:
- Helps with many types of pain;
- Available in various flavors;
- Can be taken from 3 months;
- Combined action;
- Affordable price (about 200 rubles).
Flaws:
- A clear calculation of proportions is required.
Maxicold syrup is recommended as an antipyretic for children at temperatures above 38 degrees.
Instructions for use
Taking any medications is associated with contraindications, which are indicated in the instructions.
Painkillers are no exception: just because they are sold without a prescription, this does not mean that you can take them as and when you want.
- It is unacceptable to combine alcohol and medications. Drinks containing alcohol not only enhance or weaken the effect of the drug, but can also provoke an unpredictable reaction in the body.
- Do not take tablets on an empty stomach. To preserve the stomach and intestines, you should eat a small portion of food or drink a glass of kefir. It is best to take the medicine with warm water or tea.
- The permissible dose should not be exceeded. This applies not only to daily use, but also to single use. It is best to select the dosage based on the instructions for the drug or the doctor’s recommendations. Exceeding the dose may lead to worsening of the condition and side effects.
- Different groups of painkillers should not be mixed. This can cause side effects such as dizziness and nausea, muscle cramps, general malaise and breathing problems.
- Do not overuse the frequency of administration. The body can get used to the medicine and stop coping with even minor pain on its own.
