Plasmolifting – the use of platelet membranes from blood plasma in dentistry

Taking blood plasma from a patient is a common medical procedure. In a specialized apparatus, the blood is centrifuged, separating into components: plasma - a liquid saturated with fibrin; fibrin clot with platelets and a mixture of leukocytes and erythrocytes. Plasma and fibrin clot are widely used in dentistry.

The use of platelet membranes is not an analogue of bone grafting. The volume of the jaw bone will not increase with platelets alone. Membranes are additionally used in sinus lifting, when adding bone with simultaneous implantation. This method is excellent protection after surgery. Complex surgical interventions are performed by a maxillofacial surgeon with the least amount of trauma due to the use of a piezoscalpel, which, in combination with plasma lifting, makes operations the least painful and promotes rapid recovery.

In the innovative dental clinic "Implantmaster" in Moscow, plasma lifting is carried out by highly qualified specialists. Our doctors constantly improve their professional skills and knowledge, attend office courses and seminars. Patients can always count on quality treatment. We are able to solve difficult problems in the fastest possible time and satisfy the needs of the most demanding patients, providing loyal prices for services.

In the article you will learn about plasma lifting and how this procedure is carried out. We will tell you in detail about the benefits of use. Let us introduce you to the indications and contraindications for surgical intervention using this technique.

Plasmolifting and its application in dentistry

Today, with the help of the latest “ plasmolifting ” technology in dental practice, you can get rid of bleeding gums and bad breath, and accelerate the regenerative capabilities of body tissues after surgery. The technique is actively widespread and used in many medical fields, and since 2004 it has been developed in dentistry. The founders of the technique are maxillofacial surgeons from Russia Roman Zarudiy and Renat Akhmerov.

The basis of the technique is the use of plasma produced from the patient’s own blood. The peculiarity of the procedure lies in the materials used. Blood plasma, saturated with a large number of platelets and protein cells, is otherwise called autoplasma. The material is produced in a laboratory by centrifuging blood in a special apparatus. High installation speeds separate the blood into components, the main value of which is platelets. These blood elements are responsible for regeneration and protective function in the body. Platelet autoplasma activates the regenerative potential of dental tissues and mucous membranes, reduces inflammatory processes, and enhances local immunity of the oral cavity. The effectiveness and harmlessness of the technique lies in the relationship at the biological level, as well as the complete compatibility of the components with the patient’s cells.

Along with this technique, membranes from blood plasma are used, which are implanted simultaneously with implants and enhance regenerative processes. The use of a membrane increases the rate of tissue recovery, minimizes bleeding and the likelihood of non-engraftment of the structure, and the likelihood of suture dehiscence becomes significantly less.

Plasmolifting of the gums is also used - an innovative technology for the treatment and restoration of periodontal tissues. The technique has its full name – “platelet-rich fibrin”. At the moment, the technology is dynamically used both for working with periodontium and during implant installation operations. The resulting concentrate is injected into the bone cavity where the implant will be implanted, or into the hole after the extracted tooth.

When is plasma lifting used?

• For generalized or localized periodontitis
• After difficult removal
• Upon implantation
• For gingivitis and alveolitis
• For preventive purposes

Plasma is the liquid part of the blood that contains vitamins, proteins, enzymes, and a large number of platelets.
They are necessary for healing and regeneration of damaged tissues. Therefore, plasma lifting effectively restores the structure of the gums and reduces the destructive effect on bone tissue. Plasmolifting is also important for dental health, because the gums are their support. The stability of the teeth depends on its condition.

What is platelet fibrin

Human blood contains formed elements, one of which is transparent, anucleate cells - platelets. They take part in the process of blood clotting and stopping bleeding. During the destruction of the walls of a blood vessel, platelets, disintegrating, release components that form blood clots. In the 80s, an effective function was discovered: to increase the rate of healing and tissue restoration. This process occurs due to the release of growth factors (hormonal components) that enhance the regeneration of old cells, as well as the growth and increase in the number of new cells.

Platelet autoplasma is not only formed elements, but also saturated platelet fibrin. This is a yellowish liquid released when blood is processed in a special centrifuge.

It contains:

• platelets;
• fibrin;
• fats;
• hormones;
• nucleic acids;
• mineral components.

After the autoplasma is introduced into the jaw bone, growth factors are activated within a week. The tissues are intensively saturated with oxygen, and a dense capillary network is formed. The rate of restoration of jaw bone cells and their growth, as well as tissue nutrition, increases.

Human autoplasma is saturated with nutrients and is biocompatible with the body, because it is its own product. Consequently, engraftment is successful and side effects never develop. The restoration is proceeding as planned.

Operating principle

The manipulation technique is simple. Treatment is carried out by local stimulation of regenerative processes using injections into the soft tissues of the oral cavity. The goal of such an event is not only to relieve periodontal inflammation, but also to quickly launch the processes of natural restoration of shape, color, and tissue structure. The technology prevents loss of bone tissue. Platelet-rich fibrin is a natural material. No additional agents are used to create it. It is obtained under a special processing regime. It is biocompatible with the body of the patient from whom the blood was taken.

The main component is blood cells (platelets). They contain substances rich in various growth factors, which are so necessary for other cells to recover. During therapy the following is noted:

• High efficiency of treatment;
• Absolute safety for the patient;
• No side effects or complications;
• Does not cause addiction;

Our team of doctors

Maxillofacial surgeon, Implantologist

Bocharov Maxim Viktorovich

Experience: 11 years

Orthopedist, Neuromuscular dentist

Stepanov Andrey Vasilievich

Experience: 22 years

Endodontist, Therapist

Skalet Yana Alexandrovna

Experience: 22 years

Orthopedic dentist

Tsoi Sergey Konstantinovich

Experience: 19 years

Endodontist, Therapist, Orthopedist

Varvyanskaya Anastasia Andreevna

Experience: 6 years

Dentist-orthodontist

Enikeeva Anna Stanislavovna

Experience: 3 years

Indications and contraindications for the use of plasma lifting

Indications:

• increasing the rate of tissue healing during sinus surgery and bone addition;
• recession plastic;
• treatment of periodontal diseases;
• activation of growth factors in bone cells after tooth extraction;
• implantation simultaneously with the introduction of bone material;
• various surgical interventions.

Contraindications:

• malignant neoplasms;
• systemic diseases of the blood system that do not allow plasma to be isolated or used effectively;
• decreased immunity;
• diseases in the acute stage;
• taking antibiotics;
• mental illness.

Effectiveness of the procedure

Using this technique you can eliminate:

• tooth mobility;
• bleeding gums;
• discolored periodontal tissue;
• unpleasant odor from the mouth;
• the risk of rejection of installed implants is reduced;
• pain and inflammation.

As a rule, plasma lifting is required every 3 months until a positive effect is achieved. The first results will be noticeable within 2 weeks. Despite the complete safety of plasma lifting, after the procedure you may notice swelling and bruising. You should not be afraid of these phenomena, since they will completely disappear within a few days. If other reactions occur, you should immediately inform your doctor.

Reviews about gum plasma lifting are only positive and you can see this for yourself.

Pre-registration is available at our center ☎ +7 (862) 246-35-56 or +7 (988) 400-5-666. You can also get any additional advice over the phone.

Benefits of using blood plasma

The introduction of a platelet membrane naturally activates cellular growth factors of the jaw bone and periodontal tissues, increasing the rate of recovery. Regeneration and acceptance of implants or bone material by the body is much faster, and the likelihood of inflammation is significantly minimized.

Blood plasma membranes have a positive effect on:

• increase in the rate of cellular growth factor in the bone after implantation;
• absence of allergies that could occur when interacting with foreign materials;
• accelerated gum recovery after implantation or plastic surgery;
• prevention of inflammation around the implant;
• reduction of swelling and pain after surgical procedures;
• optimal tightening of the socket after tooth extraction;
• minimizing inflammation during gingival curettage and cleaning periodontal pockets.

Stages of plasma lifting

1. Preparatory stage. Before prescribing the procedure, the doctor conducts a diagnosis of the oral cavity. If necessary, additional instrumental studies will be done and consultations with doctors of other specialties will be held. The dentist must consult the patient about the features of the procedure and preparation for it. Preparation for plasma lifting is quite simple. 7-10 days before the scheduled procedure, you must give up alcohol and smoking. In the last 3-4 days, you need to exclude fatty and fried foods from your diet. After the procedure, you also need to follow nutritional recommendations and eliminate bad habits.
2. Blood collection. It is done directly on the day of plasma lifting. After collection, the doctor processes the blood in a centrifuge to obtain plasma.
3. Plasma injection. After the plasma has been prepared, the doctor injects it into predetermined areas. Plasmolifting is carried out under local anesthesia, which eliminates any pain or discomfort during the injection.

After completion of the procedure, the dentist will give recommendations on nutrition and lifestyle. There are no complicated rules, but in order for plasma lifting to have the expected effect, you must strictly adhere to the doctor’s recommendations.

In the first 2-3 days after the plasma lifting procedure, swelling may be noticeable on the gums. Sometimes the injection site hurts a little. These phenomena are normal and go away on their own.

Preparation for plasma lifting

To carry out the innovative dental method of plasma lifting at a reasonable price, Implantmaster in Moscow has all the necessary latest equipment. Before carrying out medical manipulations, a thorough visual and instrumental examination of the oral cavity is carried out at the consultation. Next, the specialist will order an x-ray.

We perform cone beam computed tomography. The pictures are more accurate, and the Rg radiation is even less. Thanks to this, the most accurate diagnosis can be made.

Our doctors use a Labomed Magna dental microscope to thoroughly examine the condition of teeth and surrounding tissues. An examination is also carried out to determine contraindications to surgery. If no contraindications are identified, then a treatment plan is drawn up.

The doctor answers all the patient’s questions. He explains in detail the surgical procedure and schedules an appointment. To undergo the procedure as comfortably and correctly as possible, you should perform preparatory measures before performing plasma lifting:

• pre-carry out professional cleaning of the oral cavity;
• 7 days before the procedure you should not drink alcohol, heavy and spice-rich foods, or hot drinks;
• minimize smoking;
• increase the amount of water consumption to 2 liters per day;
• before treatment, do not take painkillers and drugs that affect blood clotting;
• Do not eat before the procedure.

These recommendations will allow you to carry out the upcoming procedure most effectively. And after the operation, you must follow all the specialist’s instructions.

Forecast

Inflamed tooth and gum tissues without quality therapy provokes loosening of the masticatory organs, and then their loss. Plasmolifting during tooth extraction is an important step on the path to a healthy oral cavity, which is a prerequisite for prosthetics and implantation. The cost of the procedure depends on the volume of the lesion and the characteristics of the therapy. The sooner you see a dentist, the easier and faster the treatment will be, and the more favorable the prognosis will be. Redness of the mucous membrane disappears within 3-7 hours after manipulation, swelling – within a day. Besides:

• Bleeding is eliminated;
• Periodontal diseases are prevented;
• Pain is relieved, mobility of masticatory organs is reduced;
• Breath becomes fresh;
• The gums acquire an anatomical shape and physiological color;
• The healing of the holes is accelerated;
• The progression of periodontal pathologies stops;
• The risk of pin rejection is reduced;
• Improves survival rate of rods and wound healing;

Blood substance activates the most important processes in the body - growth and regeneration at the cellular level. The result of therapy lasts for a long time, since the return of cells to a passive state takes a long time. After starting the recovery mechanism, the first results are visible in 5-7 days.

Plasmapheresis - obtaining a membrane from blood plasma

For the plasmapheresis procedure, not blood from a vein is used, but plasma from centrifuged blood. When injecting autoplasma, the tissues of the oral mucosa are saturated with nutrients. The material is otherwise referred to as “platelet-rich plasma” containing platelet concentrate.

Effectiveness is ensured by plasma with a large number of platelets in 1 μl. To achieve such saturation of the biomaterial, plasmapheresis is necessary.

1. Up to 20 ml of blood is drawn from the patient's elbow.

2. To separate the blood into its constituent components and separate unnecessary elements, it is centrifuged twice in a test tube for 15 minutes.

3. The necessary components are removed - plasma and fibrin clot.

Platelets, fibrin and biologically active substances are saturated, transforming into autoplasma. An injection is given into the marginal gum, interdental papilla or gingival projection of the tooth root.

Also, the remaining fibrin clot (membrane from blood plasma) is used for surgical interventions - osteoplasty, stimulating the healing of the hole. The shelf life of the membrane is no more than a few hours. Plasmapheresis is performed exclusively on the day of surgery. Our specialists have all the knowledge and skills to ensure technically complex operations.

Contraindications

Despite the obvious safety of such a procedure, there is a category of people for whom plasma lifting in dentistry is contraindicated. As a rule, such difficulties arise if there is the slightest risk of disruption of the plasma structure. Accordingly, such treatment will be denied:

• AIDS patients;
• with hepatitis;
• HIV-infected;
• for any blood diseases;
• for cancer of any organs;
• patients with diabetes mellitus;
• if you are allergic to heparin.

The use of membranes to add bone, during implantation, and also after tooth extraction

At Implantmaster, all surgical interventions are performed under pain relief using anesthesia. Our specialists perform atraumatic removal of all teeth, even multi-rooted ones.

The maxillofacial surgeon, implant surgeon, in order to prevent breakage of the partition between the roots, separates them from each other. Using a periotome, the marginal gum is gently moved away from the tooth to preserve its integrity. Next, using an innovative piezo scalpel - the VarioSurg LED ultrasonic surgical system from NSK (made in Japan) - the roots are separated and their subsequent segmentation is carried out. Removal becomes safe, painless and as comfortable as possible for the patient. Ultrasound manipulation has an antiseptic effect and in the future you can do without taking antibiotics. The risk of infection and complications in the oral cavity is reduced. Immediately after ultrasound exposure, it can be implanted. Our highly qualified specialists use the latest materials and technologies, such as Straumann or Osstem implants. Their osteointegration takes place in 3-5 weeks, and they can also be installed when the bone level is small.

Subsequent application of platelet membranes containing cell growth factors accelerates regeneration. During surgery, the membrane covers the defect, implanted bone material or artificial root. Sometimes a fibrin clot is combined with the patient's bone material and introduced into the defect area. Afterwards, suture material is applied.

If the membrane was installed to prevent alveolar inflammation after removal, then sutures are not applied. It is not advisable to rinse your mouth during the first 3 days.

Possible risk during the procedure

Plasmolifting is a safe and effective treatment method. But like any medical procedure, it should be carried out only by an experienced doctor in compliance with all stages of the protocol. A preparatory stage is required, which allows you to assess the quality of the patient’s blood.

It is important to maintain the sterility of instruments both when processing biomaterial in the laboratory and when introducing plasma into soft tissues. The technical equipment of the dental clinic deserves special attention. Without the availability of modern equipment, it will be problematic to create concentrated plasma without pathogenic microorganisms entering it. That is why this procedure is not performed in all dentists.

Trust between doctor and patient is also important. It is imperative to report all chronic diseases, hidden infections and medications. All this can affect the condition of the blood, and therefore the effectiveness of the procedure.

If you cannot get rid of inflammation and bleeding gums for a long time, then contact Mitino dentistry for a consultation. Our medical center has its own technically equipped laboratory, and our doctors are fluent in all modern methods of dental treatment.

Recommendations after plasma lifting

Plasmolifting is carried out in combination with other medical procedures. The duration of the rehabilitation period is determined depending on the disease and the medical procedures performed.

Recommendations for the patient to follow after treatment:

• limit physical activity during the recovery period;
• avoid exposure to high and low temperatures - baths, saunas, solariums;
• do not disturb the intervention site with your tongue and brush;
• maintain proper oral hygiene;
• temporarily eliminate hard and irritating foods and alcohol consumption.

What is the effect of plasmolifting gums

• Relieves bad breath
• Eliminates bleeding
• Reduces tooth mobility
• Restores gum color and structure
• Accelerates the healing process
• Relieves inflammation
• Reduces the risk of implant rejection
• Strengthens bone tissue

Plasmolifting in the complex treatment of periodontal diseases is carried out after professional hygiene and relief of acute inflammation.