Which is better to choose Cholisal or Metrogyl Denta: review of drugs, instructions for use, effectiveness and reviews

Cholisal or Metrogyl Denta are two of the most popular dental products, produced in the form of gels and prescribed to relieve inflammation, pain and swelling. But these drugs differ in their scope of application, since they exhibit activity against different types of pathogenic microbes. Therefore, it is recommended to use them according to individual indications and after the recommendation of a doctor.

Cholisal or Metrogyl Denta are dental products produced in the form of gels and prescribed to relieve inflammation, pain and swelling.

Gel Metrogyl Denta: pharmacological description

Metrogyl Denta is a gel for external use with anti-inflammatory and antimicrobial effects. It contains two active components - the antibiotic metronidazole and chlorhexidine, which determine the therapeutic effect of the gel.

When applied, metronidazole as part of the drug destroys pathogenic microorganisms not only on tooth enamel and gums, but also on the mucous membranes of the cheeks and tongue. It is effective against most known gram-positive and gram-negative bacteria. Chlorhexidine has a pronounced antiseptic and antimicrobial effect.

The gel is used only in dental practice - it is intended exclusively for external application, is not absorbed into the systemic bloodstream, acting directly on the source of inflammation.

Metrogyl is also available in the pharmacological form of a solution intended for intravenous administration. Metrogyl solution has other indications for use - it is prescribed for the treatment of diseases of bacterial origin.

Indications for use of the gel

The drug is prescribed in the complex treatment of a wide range of dental diseases. It is recommended for use in the following cases:

• with aphthous stomatitis;
• for acute or chronic gingivitis;
• with Vincent's ulcerative-necrotizing gingivitis;
• with periodontal disease;
• for periodontitis;
• with cheilitis.

The pharmacological agent is prescribed for the treatment of inflammatory processes in the oral cavity that develop against the background of prolonged wear of dental processes or damage to the socket after tooth extraction (post-extraction alveolitis). Dental gel can be used at any stage of an inflammatory and infectious disease.

The ointment can be combined with other antiseptic and medicinal drugs, since it does not interact with them.

The pharmacological agent can be used not only for treatment, but also for the prevention of dental diseases. It quickly eliminates redness and swelling, reduces the sensitivity of nerve roots, saturates the affected tissues with nutritious active substances and accelerates natural cell regeneration.

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Properties of drugs

The main purpose of these drugs is to destroy harmful microorganisms. To do this, simply apply the gel to the gums, and the active ingredients will have an antimicrobial, antibacterial and antiseptic effect. An important advantage of Metrogyl and Cholisal is that their components do not have side effects on internal organs, while effectively removing the cause of pathology and helping to increase local immunity (resistance of the oral mucosa to infections).

Holisal

Cholisal is a drug produced in Poland, widely prescribed in dentistry, and has the appearance of a transparent composition with an anise scent. The gel includes 2 active ingredients - cetalkonium chloride and choline salicylate. Cetalkonium chloride is an antiseptic; it destroys pathogenic fungi, viruses and bacteria. Choline salicylate, by inhibiting the activity of COX and inhibiting the synthesis of prostaglandins, solves a whole range of problems:

• relieves pain
• relieves inflammation
• lowers fever.

The gel base of the drug ensures rapid distribution of the drug throughout the mucous membrane, penetrates into the gum tissue, which ensures long-term retention of the active substance at the pathogenic site. The analgesic effect occurs within 3 minutes, maintaining the reaction for up to 8 hours. Cholisal does not contain sugar, does not have irritating properties and is well tolerated by patients with the following diseases:

• stomatitis (ulcers that form on the oral mucosa and tongue),
• candidiasis (inflammation caused by yeast-like fungi Candida),
• gingivitis (inflammation of the gums that does not affect the periodontal junction),
• periodontitis (a progressive form of gingivitis that affects the tissue around the tooth; in the acute form, teeth may become loose and fall out),
• cheilitis (painful inflammatory sores and crusts on the lips),
• exudative erythema multiforme,
• injury to the gums due to dentures (other damage to the mucous membrane),
• postoperative swelling and pain in the gum area,
• teething in children.

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Cholisal does not contain sugar, has no irritating properties and is well tolerated by patients.

The medicine is applied 3 times a day, 20 minutes before meals or immediately after meals (after thoroughly rinsing the mouth), distributed with light movements, and the last application is done at night. Cholisal is not indicated for individual intolerance and for children under 1 year of age. Prescription to pregnant and lactating women is allowed, but in agreement with the gynecologist.

Metrogil Denta

The therapeutic effect of this Indian-made gel is determined by its composition, which includes 2 active substances - the antibiotic metronidazole (in the form of benzoate) and the antiseptic chlorhexidine bigluconate (20% solution). Metronidazole benzoate, easily penetrating into saliva, destroys bacteria and creates a high-concentration bactericidal barrier. Chlorhexidine digluconate kills protozoan pathogenic microorganisms and the herpes virus.

The drug retains its activity even with purulent discharge, without affecting the properties of beneficial lactobacilli.

The gel has low absorption and has the principles of local action:

• antiseptic,
• disinfecting,
• anti-inflammatory,
• cleansing.

Prescribed for the following pathologies:

• stomatitis (aphthous and candidal),
• gingivitis (chronic, acute, ulcerative-necrotic),
• periodontitis,
• cheilitis,
• periodontal disease (impaired blood supply to the gum tissue that holds the tooth),
• periodontal abscess (painful foci of purulent inflammation, accompanied by swelling and loosening of teeth),
• post-extraction alveolitis (inflammation of the wound that occurs at the site of an extracted tooth),
• various mucosal injuries.

The gel is applied superficially or in the form of applications 2 times a day after thoroughly cleaning the mouth. The course of treatment is 1-2 weeks (until the symptoms disappear and another 2 days after, but not longer than 14 days). Metrogyl is not indicated for cases of individual intolerance, pregnancy and lactation, and children under 6 years of age.

Metrogyl is not indicated for cases of individual intolerance, pregnancy and lactation, and children under 6 years of age.

Metrogyl solution - features and action

Metrogyl solution is a drug based on the antibiotic metronidazole, intended for the treatment of many diseases caused by gram-positive and gram-negative bacteria.

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The pharmacological agent in the form of a solution has antibacterial, antiprotozoal and trichomonacid effects. The solution not only inhibits the development of infection, but also increases the sensitivity of tumors and bacteria to radiation, stimulating differentiating processes in the body.

Droppers with medicine are most often prescribed for severe forms of infectious diseases, regardless of their nature, as well as in cases where it is impossible to take an antibiotic orally. The course of treatment with an antibacterial solution lasts from 7-10 days to several weeks.

The initial dosage of an intravenous drip is no more than 1 g, which is administered over half an hour. After this, a break is taken for 8 hours, then the drug is administered in a dosage of ½ g at a rate of 5 liters for 60 seconds.

Indications for use of the dropper

Metrogyl dropper, the indications for use of which are radically different from dental gel, is effective against many diseases caused by pathogenic microorganisms. These include Trichomonas, Gardnerella, coccoid and anaerobic bacteria. Droppers with medicine are prescribed in the following cases:

• giardiasis;
• intestinal dysentery;
• invasive lesions of the genitourinary system;
• vaginitis and trichomonas urethritis;

• giardiasis;
• Borovsky's disease;
• quinsy;
• parasitic skin lesions;
• infectious diseases of joints and bone tissue;
• bacterial endocarditis;
• ulcerative colitis and inflammatory damage to the mucous tissues of the stomach;
• inflammation of the tissues of the spinal cord and brain;
• death of tissues and cells of the lungs and brain;
• infectious diseases of the pelvic and intestinal organs, accompanied by stool disorders.

Also, intravenous administration of Metrogyl solution is prescribed for the prevention and complications of infection after surgical treatment of gynecological diseases and diseases of the gastrointestinal tract.

Main contraindications to the use of gel and dropper

Dental gel has a small number of contraindications for use. These include:

• for children under 6 years old;
• with hypersensitivity to metronidazole;
• in case of individual intolerance to active components.

The gel is approved for use during pregnancy, as it does not penetrate the systemic bloodstream and does not cause any harm to the fetus. But it is best to carry out treatment under the supervision of a doctor, since the risk of an allergic reaction cannot be ruled out.

Metrogyl solution for intravenous administration has a significantly larger number of contraindications for use. These include:

• epilepsy and other organic lesions of the central nervous system;
• renal and liver failure;
• diseases of the hematopoietic system;
• first trimester of pregnancy;
• breastfeeding period.

Also, intravenous injections are prohibited in case of individual intolerance to the active components included in the drug.

Side effects of the gel and dropper

In most cases, Metrogyl Denta gel is well tolerated and does not cause side effects. In some patients, the use of the medicine provokes attacks of severe headaches, skin rashes, accompanied by itching, burning and other unpleasant sensations. In such cases, an analogue is selected.

When administered intravenously, Metrogyl causes side effects much more often. The most common ones include:

• increased dryness of the skin;
• deterioration of appetite until it completely disappears;
• attacks of nausea;
• bloating, painful stomach cramps;
• unpleasant metallic taste in the mouth.

Much less often, a Metrogyl dropper causes attacks of vomiting, prolonged constipation, dizziness, sleep disturbances and coordination of movements. Increased fatigue, lethargy or hyperactivity, frequent and spontaneous urination, change in urine color and the development of thrush are also possible.

Symptoms

The inflammatory process manifests itself as follows:

• The gums turn red and become unnaturally soft when touched.
• Uncontrollable bleeding appears.
• The cervical area is exposed, the teeth seem longer than usual.
• Loosening begins.
• Chewing food becomes painful, any touch causes discomfort.
• Bad breath does not go away even after regular brushing.

If, against the background of symptoms, a doctor diagnoses gingivitis, then it comes in three types:

• Catarrhal - redness is accompanied by itching and aching, prolonged pain.
• Ulcerative - resembles aphthous stomatitis, but with a large number of characteristic whitish lesions. It is extremely painful.
• Hypertrophic - gum tissue grows to large sizes under the influence of hormones. In most cases it is treated with surgery.

If the patient has crowns installed, this complicates the diagnosis and further treatment of inflammation. In some situations, dentures must be removed in order for therapy to proceed properly.

Cholisal - pharmacological description

Cholisal is a dental gel based on choline salicylate. The drug has a local antipyretic, analgesic, antimicrobial and anti-inflammatory effect.

Cholisal is widely used in dental practice for the treatment of inflammatory periodontal diseases that occur with pain, redness and bleeding. The main indications for use of the drug are:

• gingivitis;

• periodontitis;
• stomatitis of various origins;
• cheilitis;
• injury to the oral mucosa when wearing dentures;
• thrush of the oral mucosa.

Cholisal is often prescribed to eliminate pain and other unpleasant symptoms during teething in children, recovery after surgery, as well as in the complex treatment of lichen planus and Stevens-Johnson syndrome localized in the oral cavity.

Gel Cholisal has virtually no contraindications. It should not be used only in case of hypersensitivity to the active components included in its composition. Treatment of children under 12 months of age is carried out only as prescribed and under the supervision of a pediatrician.

Reviews from doctors

Mikhailov S.P., orthopedic surgeon, Saratov

Of the two products, I recommend Cholisal gel. In addition to all the listed advantages, this drug, which does not contain sugar, is indicated for patients with diabetes.

Istratova N.D., therapeutic dentist, Moscow

Everyone now has problems with gums, but patients do not pay attention to it until the situation escalates to an inflammatory process. The simplest oral care is rinsing after every meal. And if a pathology is identified, then Cholisal can help and read the annotation.

Smirnov A.V., dentist (surgeon), Penza

Dental diseases come in many varieties. Self-treatment is unacceptable. It is not enough to read the instructions; it is important to understand the form of the pathology, and only a doctor will determine this.

Dentamed dental gel – characteristics

Dentamed is a drug in the form of a gel intended for external use in dental practice. The pharmacological agent has an identical composition to Metrogyl Denta gel, which is based on the active substance metronidazole in combination with the antiseptic chlorhexidine.

Dentamed has a pronounced antimicrobial, disinfectant, anti-inflammatory and antipyretic effect. The medication is used to treat various dental diseases - gingivitis (chronic, necrotic, atrophic, hyperplastic), periodontitis, stomatitis, pulpitis.

Dentamed should not be used in case of hypersensitivity to metronidazole or chlorhexidine, or for the treatment of children under 6 years of age. The product is used with extreme caution and only under the supervision of a physician during pregnancy and breastfeeding.

The dental drug is well tolerated by the body. In rare cases, an unpleasant, “metallic” taste in the mouth, redness, itching and burning at the site of application may occur.

Composition and release form

Cholisal is a colorless transparent gel which contains: choline salicylate and cetalkonium chloride. Excipients: methyl parahydroxybenzonate, glycerol, ethanol, hyaetellose, anise seed oil, water. The gel is well absorbed into the oral cavity, is well tolerated by patients, and does not contain sugar.

Packaged in an aluminum tube with a cap made of polymer material, 10, 15 g each. One piece in a cardboard box.

Metrogyl denta is a gel-like opalescent preparation of white or almost white color. It contains: metronizadol benzoate and chlorhexidine bigluconate.

Excipients:

• propylene glycol;
• disodium edate;
• levomenthol;
• water;
• carbomer, sodium saccharinate, sodium hydroxide.

These drugs can be purchased without a doctor's prescription. The shelf life allows them to be stored for three years, at a temperature not exceeding 25 degrees.

Dental adhesive paste Solcoseryl

Solcoseryl is a drug that is available in three pharmacological forms - a facial gel for acne, an ointment and a dental adhesive paste intended for the treatment of dental diseases.

Dental adhesive paste Solcoseryl is used as a local anti-inflammatory and analgesic agent, a fast-acting stimulator of tissue regeneration. It is most effective in the treatment of seizures, blistering lesions of the oral mucosa, periodontal diseases, gingivitis, periodontitis, stomatitis and alveolitis.

The difference between dental adhesive paste and its analogues is that it forms a thin protective film on the treated surface, which prevents tissue injury for 4-6 hours.

Solcoseryl is well tolerated by the body, therefore it is approved for use in infancy. In very rare cases, dental adhesive paste can cause redness, swelling, burning at the application site, as well as local allergic reactions.

Cheap and effective analogues

Cheap analogues of Metrogyl Denta are prescribed if the use of the drug is impossible due to existing contraindications or it causes side effects. The most popular and widespread analogues include:

To choose the most effective analogue of dental gel, it is best to consult a doctor, since all the pharmacological preparations presented differ not only in cost and manufacturer, but also in their mechanism of action.

Which is better - Metrogyl Denta or Cholisal

In order to answer the question of Cholisal or Metrogyl Denta, which is better, you need to compare the pharmacological characteristics of the drugs, as well as the indications for their use. These medications differ in their range of applications and the power of their therapeutic effects.

One of the main differences between the drugs is that Cholisal is often prescribed by pediatricians to alleviate the condition of a child during teething - it is approved for use from infancy, Metrogyl Denta can only be used for children over 6 years of age.

Both drugs relieve inflammation in the oral cavity. Cholisal acts directly on the mechanism of the inflammatory process, inhibiting the production of the enzyme cyclooxygenase, which causes pain and other unpleasant symptoms. The action of its analogue is only to prevent the growth and reproduction of pathogenic bacteria.

Many dental diseases develop against the background of the activity of infectious pathogens - streptococci, staphylococci, enterococci. These microorganisms are opportunistic and most often become active when immunity decreases. In some cases, oral diseases can be caused by viruses or fungi. Cholisal has a wider spectrum of action than its analogue - it effectively fights viral, infectious and fungal pathogens.

Metrogil Denta or Dentamed

Dentamed or Metrogyl Denta, which is better, depends on the indications and contraindications for use, since each of these drugs has its own spectrum of therapeutic action.

Dentamed and its analogue have both similar and distinctive features:

1. Both drugs are available in the form of a dental gel. Metrogyl Denta has a denser and thicker consistency, Dentamed is more liquid.
2. Dentamed has an unpleasant, bitter taste.

3. Pharmacological preparations have an identical composition, which includes the antibiotic metronidazole and the antiseptic substance chlorhexidine. But they contain different auxiliary components.
4. The cost of Dentamed is almost two times lower than its analogue.
5. Dentamed has only one contraindication for use - hypersensitivity to the components that make up its composition.

Metrogyl Denta and Dentamed have the same therapeutic effect and identical composition, therefore, when choosing a dental gel, you need to take into account age restrictions (Dentamed is allowed to be used for newborns) and possible side effects (Dentamed causes allergies much less frequently than its analogue).

Can Solcoseryl replace Metrogyl Dent?

Solcoseryl is a drug that is available in three pharmacological forms - a facial gel for acne, an ointment and a dental adhesive paste intended for the treatment of dental diseases.

Solcoseryl differs from its analogue in composition - the main active substance in it is dialysate from the blood plasma of dairy calves. The drug is used in the treatment of painful, bleeding ulcers and wounds in the mouth.

It accelerates natural tissue regeneration, scarring of microcracks, activates healing after tooth extraction, as well as damage caused by wearing dentures. Both drugs have similar therapeutic effects - regenerating, wound healing, anti-inflammatory, antimicrobial and antiseptic.

Dentists emphasize that Solcoseryl has a wider spectrum of action - in addition to restoring the mucous tissues of the oral cavity, it also accelerates the healing of the skin.

Dental adhesive paste Solcoseryl has virtually no contraindications for use (except for individual intolerance), does not cause an overdose and extremely rarely causes an allergic reaction. The advantage of Solcoseryl is that it can be used during pregnancy, breastfeeding, and also for newborns. Its analogue is not used for this category of patients.

How they work and their differences

These drugs have a wide range of effects on diseases:

• suppress the inflammatory process and swelling, eliminating the feeling of discomfort;
• nourish the gums with biologically active substances;
• accelerate the recovery of injured cells;
• Immunity is significantly increased, increasing the resistance of bacteria, viruses and fungi found in the oral cavity.

This significantly reduces the risk of recurrence of these diseases.

Cholisal is the best option for treating gums. Its spectrum of action is wide: it eliminates painful symptoms, eliminates microbes, relieves inflammation, and has antipyretic properties.

Metrogyl denta is also an antiseptic, but unlike cholisal it acts only on the surface of the gums and it contains much less metronizadol, which has antimicrobial properties.

Main conclusions

Metrogyl Denta is a medicinal product in gel form intended for the treatment and prevention of many dental diseases. The gel quickly eliminates redness, swelling and bleeding of the gums, stops inflammatory and infectious processes, and prevents further growth and reproduction of pathogenic microorganisms.

Dental gel should not be used for children under 6 years of age, during the first trimester of pregnancy and breastfeeding. The pharmacological drug must be used very carefully, following the instructions, as it can cause a number of side effects. In such cases, it is best to replace the dental gel with safer and no less effective analogues, which include Cholisal, Dentamed and Solcoseryl.

How to treat gum disease

Treatment of sore gums

Before the dentist prescribes a treatment program, it is necessary to undergo a diagnosis:

1. General visual examination of the oral cavity for caries and other related diseases.
2. Palpation of gums, periodontal zones, identification of painful reactions.
3. Sight X-ray or panoramic tomography of the jaw.

When the diagnosis is made, carious and allergic factors are excluded, the patient is prescribed home treatment, which includes:

• Daily rinsing with antiseptic solutions (chlorhexidine, miramistin and their analogues).
• Antibacterial and analgesic ointments and gel (Cholisal, Kamistad, Metrogil-denta, etc.).
• If necessary, a course of antibiotics and antihistamines to stop the further spread of inflammation.

Surgical intervention is required only for hypertrophic forms of gingivitis, a detected dental cyst or purulent periostitis. In other situations, doctors try to avoid invasive methods so as not to injure the gum tissue even more.