Gel "Metrogil Denta": composition, instructions for use


To treat inflammatory diseases of the oral cavity, it is recommended to use effective means, for example, the inexpensive Metrogyl Denta gel. It is used for the prevention and treatment of gingivitis, stomatitis, periodontal disease and other dangerous pathologies. The drug is characterized by rapid action and minimal likelihood of side effects. Sold in pharmacies without a doctor's prescription.

Gel "Metrogil Denta": description, composition

The drug is available in the form of a gel, which is packaged in plastic tubes of various sizes. The active ingredients are chlorhexidine and metronidazole.

It has high antimicrobial activity due to the presence of 2 substances in its composition. The following additional compounds are used: propylene glycol, water, sodium in the form of hydroxide, others.

The product is stored under normal room conditions at temperatures up to 25 degrees Celsius. It is important to protect from direct sunlight and prevent children from accessing it. The shelf life of the gel is 3 years from the date of production. After this time, the drug cannot be used.

Pharmacodynamics

The drug has a combined effect, since it contains 2 active components with an antibacterial effect:

  1. Chlorhexidine acts on a wide class of gram-negative and gram-positive bacteria. At the same time, it does not inhibit the vital activity of beneficial lactobacilli.
  2. Metronidazole destroys bacteria that live in an oxygen environment, i.e. aerobic microorganisms. They are the ones that cause periodontal disease.

The gel is used topically, so its active components are practically not absorbed through the walls of blood vessels and do not enter the bloodstream.

Description of the drug

If, during dental treatment, the doctor diagnoses gum inflammation, the patients are prescribed antimicrobial drugs. Metrogyl Denta is active against most infectious agents of dental diseases. These are gram-negative and gram-positive anaerobes and aerobes, some types of protozoa. Course use of the drug is recommended for the following purposes:

  • prevention of active growth and reproduction of pathogenic microorganisms and their complete destruction;
  • preventing the spread of the inflammatory process to healthy tissues of the oral cavity.

Metrogyl Denta is prohibited for use in the first trimester of pregnancy.

Its use is possible only during periods of intensive fetal growth. When the child’s organs are already formed, the ingredients of the drug do not have a negative effect.

pharmachologic effect

Patients often ask dentists whether pregnant women can use Metrogyl Denta gel.
It contains metronidazole, which is not advisable to use while pregnant. But if the dosages are observed, the chemical compound practically does not penetrate into the systemic bloodstream. The action of Metrogyl Denta is based on the pharmacological properties of its ingredients. During biochemical reactions, the nitro groups of metronidazole molecules are restored. This process occurs with the participation of intracellular transport proteins:

  • protozoa;
  • anaerobic bacteria.

After reduction, nitro groups are integrated into the DNA chains of microorganisms and begin to inhibit the biosynthesis of nucleic acids. As a result, bacteria lose their ability to grow and reproduce, which causes their death. Metrogyl Denta exhibits bactericidal activity against the following infectious agents:

  • Borrelia vincenti;
  • Fusobacterium fusiformis;
  • Eikenella corrodens.

Chlorhexidine exhibits pronounced antiseptic activity. Dissociation of its salt occurs with the formation of cations. They react with bacterial cell walls and disaggregate them. As a result, the osmotic balance is disrupted, the cytoplasmic membranes are destroyed, and the microbes die.

Release form and composition

Metrogyl Denta is produced in India. It is produced in the form of a gel of thick consistency, opalescent, white, with a pleasant menthol odor. The drug is packaged in 5.0 g, 10.0 g, 20.0 g in soft plastic tubes. In addition to metronidazole and chlorhexidine, it contains the following ingredients:

  • levomenthol;
  • propylene glycol;
  • carbopol;
  • purified water;
  • sodium saccharinate;
  • sodium hydroxide;
  • disodium salt of ethylenediaminetetraacetic acid.

Due to the content of levomenthol in the gel, after its application you feel coolness, pain and burning disappear. And propylene glycol and carbopol ensure rapid absorption of ingredients into the mucous membranes of the oral cavity. Secondary packaging of Metrogyl Denta is a cardboard box with an attached annotation. The shelf life of the drug is 36 months. The dental product must be stored in a place protected from light at a temperature not exceeding 25°C. The average cost of 20.0 g in pharmacies is 260 rubles.

Indications for use

The drug is used for various inflammatory pathologies occurring in the oral cavity:

  • gingivitis in the acute and chronic stages;
  • Vincent's gingivitis in acute form;
  • periodontitis in acute and chronic form;
  • aphthous stomatitis;
  • juvenile prodontitis;
  • periodontal disease as a complication of gingivitis;
  • cheilitis;
  • inflammation of the oral mucosa as a complication after using a prosthesis;
  • alveolitis of post-extraction type;
  • periodontitis, abscess.

Contraindications and side effects

In some cases the gel cannot be used:

  • individual sensitivity to any component of the drug;
  • blood diseases, including in the past observation;
  • pathologies of the central and peripheral nervous system;
  • children up to 17 years old inclusive.

During pregnancy and lactation, the use of the gel is allowed with caution. A preliminary consultation with a doctor is recommended. Admission is carried out only if the expected benefit is greater than the potential risks.

When taking the drug, skin rashes, itching, headaches, redness, hives and other allergic reactions are possible. In this case, it is recommended to stop treatment and consult a specialist for advice. You may need to change the drug.

Is it possible to use Metrogyl Denta during pregnancy?

Metrogyl Denta is a medicine whose course use helps restore gum health. This ability of the gel is especially in demand during pregnancy. A woman’s body experiences excessive stress due to changes in hormonal levels, which provoke calcium deficiency. And a decrease in immunity often leads to the activation of bacteria belonging to an opportunistic biocenosis. They cause the development of oral pathologies and deterioration of the gums and teeth. Metrogyl Denta successfully copes with all negative symptoms:

  • heavy dental plaque;
  • redness and swelling of the mucous membranes;
  • bleeding even with a light touch;
  • burning, stinging and pain during eating.

The dental preparation not only eliminates clinical manifestations, but also affects the cause of the disease - pathogenic microorganisms. Therefore, when asked by pregnant women whether Metrogyl Denta can be used, doctors answer positively. But not during the first trimester of pregnancy, when the formation of the fetus begins.

Potential Harm

During pregnancy, you can use Metrogyl Denta after the end of the first trimester. According to the results of clinical studies, it is safe during this period for the intrauterine development of the fetus. If a woman used the drug for preventive purposes before conception, it is now better to abandon it. Any pharmacological load is undesirable during the period of bearing a child. To prevent the development of gingivitis or periodontitis, you can rinse your mouth with infusions of medicinal herbs:

  • chamomile;
  • sage;
  • oak bark.

In the early stages of pregnancy, the internal organs of the fetus are just beginning to form, the kidneys and stomach are just beginning to function. Metrogyl Denta contains two ingredients that are not antibiotics, but have their properties. Therefore, there is a potential for the development of congenital anomalies.

In the first trimester of pregnancy, you should take any medications only as prescribed by your doctor.

At the first symptoms of gum disease, you should contact your dentist as soon as possible. Treatment of periodontitis or stomatitis at the initial stage is often done without the use of drugs.

Instructions for use of gel "Metrogil Denta"

The drug is used only locally, without oral administration. The instructions depend on the indications:

  1. In case of inflammation, the gel is applied to the surface of the gums in a small layer. This can be done with a clean finger or a sterile cotton swab. The procedure is repeated 2 times a day. The medicine cannot be washed off, so you should avoid contact with water, food and drinks for half an hour after taking it. Therapy is continued for 7-10 days.
  2. To treat periodontitis, the affected surfaces must be treated with a gel application. This can be done in a clinic or on your own. The layer needs to be applied for 30 minutes. The procedures are carried out several times until complete recovery. As a rule, 2 times a day for 7-10 days is enough.
  3. In the case of aphthous stomatitis, the affected areas of the mucous membranes are coated with the composition 2 times a day for 7-10 days.
  4. To prevent chronic gingivitis, the gel should be used in the same way - it is applied to the gums 2 times a day, treatment is continued for 1 to 1.5 weeks. The same cycles are repeated 2-3 times a year.
  5. To prevent post-extraction type alveolitis, the cavity after the extracted tooth is coated with gel 2 or 3 times a day for 1-1.5 weeks.

Instructions for use

In the later stages of pregnancy, the dentist prescribes it when infectious and inflammatory pathologies of the mouth are detected. A woman should not ignore medical recommendations. Any untreated infection will cause symptoms of general intoxication of the body. Such an action will negatively affect the intrauterine growth and development of the fetus and harm the health of the mother.

The duration of therapy recommended during pregnancy in the instructions for use of Metrogyl Denta is 5-14 days. When carrying a child, the drug is prescribed for the shortest possible time and in low doses . This helps minimize the likelihood of side effects. Breastfeeding should be discontinued during treatment with dental gel.

Indications and contraindications

A contraindication to the use of Metrogyl Denta during pregnancy is intolerance to the active or auxiliary ingredients. Also, it cannot be used to prevent gingivitis and other dental pathologies. The gel is prescribed to patients when diagnosing the following periodontal diseases:

  • Vincent's ulcerative necrotic gingivitis;
  • post-extraction alveolitis;
  • acute or chronic periodontitis.

The drug is used to treat cheilitis - inflammation that affects the red border, mucous membrane and skin of the lips. It quickly destroys infectious agents of stomatitis, especially its aphthous form.

Scheme of use during pregnancy

From the second trimester of pregnancy, a thin layer of Metrogyl Dent should be applied to the gums in the morning and evening. The procedure should be carried out only with clean hands using a cotton pad or swab.

After application, you should refrain from eating food and water for 30-40 minutes.

If periodontitis is detected during pregnancy, then Metrogyl Denta gel is used after cleaning the tartar. The dentist will show the woman how to treat a periodontal pocket. In the future, she carries out the procedure independently at home. The average duration of use is 7-10 days.

Side effects

In the second and third trimesters of pregnancy, the use of Metrogyl Denta may cause the development of allergies. Clinically, it manifests itself in the form of small rashes, itching, swelling and redness of the skin.

special instructions

The drug has an antiseptic effect and disinfects the oral cavity well. However, its use does not replace the need to brush your teeth, which should be done as usual 2 times a day - in the morning and before bed.

If the gel is accidentally ingested (can be swallowed by a child), you should immediately seek emergency help. You may need gastric lavage and appropriate medications.

After the expiration date, the remaining product should not be thrown into the sewer or as garbage on the street. It is placed in a tight bag and then thrown into a trash container.

There is no data on the effect of the gel on the speed of psychomotor reactions. Therefore, it can be used by drivers and other workers whose activities involve the need to make quick decisions.

Treatment of hypertrophic gingivitis

Therapy includes all of the above methods. If the cause of gum overgrowth is traumatization of the gums by the overhanging edges of crowns and fillings, their shape is corrected. In severe cases of the disease, sclerosing therapy (injections of sclerosing solutions into the gingival papillae) may be prescribed. Also, in some cases, the gingival margin is corrected surgically. This treatment is prescribed after childbirth. Only a doctor can select adequate therapy.

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The information in this article is for reference only and does not replace professional advice from a doctor. To make a diagnosis and prescribe treatment, consult a qualified specialist.

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