Antibiotics prescribed for infectious diseases

inflammation of the appendages
Ultrasound tests

Various groups of microorganisms can lead to an inflammatory process in the appendages. These include: chlamydia, trichomonas, mycoplasma and ureaplasma, gonococci, staphylococci, streptococci and others. When diagnosing acute inflammation of the appendages, doctors prescribe antibacterial therapy, which is the preferred method of treatment. However, in certain situations, antibiotics are prescribed, for example, for recurrent inflammation.

How to choose an antibiotic for adnexitis?

Acute adnexitis (inflammation of the appendages) requires immediate treatment with antibiotics. There is no need to wait for tests to begin the treatment process. It is recommended to select antibiotics with a wide range of indications that even act on intracellular pathogens, which include mycoplasmas and chlamydia.

Fluoroquinolones and tetracyclines meet similar requirements. These are effective medications that help in the treatment of adnexitis. Then, after receiving the test result, the specialist determines the type of pathogen and can adjust the treatment program. This is especially true if the prescribed drugs do not have a beneficial effect on the patient. In some cases, it is impossible to get by with just one type of antibiotic. However, complex treatment with different drugs that can disrupt the active life of different groups of pathogens may be required.

Tetracyclines

These drugs are used to treat inflammation in the appendages. But the sensitivity of infectious pathogens to the drug is lost as antibiotics are taken. Tetracyclines have severe side effects.

The most popular drug from this group is doxycycline, which has minimal side effects and is quickly eliminated from the body. Solutab is a good remedy. Its active substance is placed in microspheres filled with a special filler. Under its influence, microspheres dissolve in an alkaline environment, and not in an acidic one.

Myths and facts about antibiotics

Antibiotic therapy, like vaccinations, is shrouded in myths, fears and stories of how someone lost their hearing after treatment with antibiotics, got a persistent intestinal disorder, and in general, antibiotics are too dangerous because they kill all living things.

Briefly: yes, antibiotics have serious side effects and, if prescribed incorrectly, can actually cause hearing problems, etc. There are drugs prohibited for children and pregnant women, but in general modern drugs are safe if taken as directed. And now in more detail

Immune status

When it is not possible to make an accurate diagnosis, the disease is long-lasting and difficult, it is necessary to find out the state of the immune system. These surveys are lengthy and expensive. Express diagnostics allows you to obtain general data in order to conduct more in-depth research without unnecessary expenses.

A little history:

At the end of the 19th century, several scientists immediately noticed that penicillin fungus mold accelerates the healing of wounds, but its use was difficult - even with short-term storage, the beneficial properties of the mold were lost. In 1938, scientists from Oxford isolated penicillin in its pure form, for which they received the Nobel Prize. And Zinaida Ermolyeva is considered the mother of domestic antibiotic therapy - in 1942 she developed the first Soviet antibiotic, Krustozin, which immediately found use in military hospitals - mortality from bacterial complications fell sharply. Today there are a great variety of antibiotics; there are even drugs with a cytostatic effect that stop the growth of tumor cells.

The most popular question: are antibiotics and alcohol compatible?

Briefly: there are antibiotics that can be taken with alcohol, and there are those where drinking alcohol is contraindicated. In general, it is better not to stop antibiotic therapy because of a glass of wine, but to abstain from alcohol throughout the entire treatment phase.

Read more: it is better to avoid drinking alcohol during treatment, but for most antibiotics it makes no difference whether you drank or not. However, there are exceptions: some drugs slow down the breakdown of alcohol, this increases the concentration of acetaldehyde, causing unpleasant symptoms, including vomiting. Previously, alcoholism was treated with such antibiotics. Where do the roots of this myth come from: during the war, the production of antibiotics was too expensive, they were isolated repeatedly from the urine of patients, and since beer increased the volume of urine and complicated the process, drinking was banned. Another opinion is that venereologists, when prescribing antibiotics, forbade drinking in order, firstly, to punish patients, and secondly, to reduce the likelihood of accidental contacts and further spread of infection.

Conclusion: it is better to give up alcohol so as not to increase the load on the liver and other organs.

Do you have to complete the course to the end?

Complex issue. Modern pharmacology strives to reduce the time of taking the drug while maintaining the effect. Today, single-dose antibiotics have been developed. Previously, it was believed that by not drinking the course to the end, we increase the resistance of microorganisms. But she appears anyway. Studies have confirmed that a short “impact” course is no different in effectiveness from a long one, and resistance is reduced. Most likely, this is due to the fact that resistant bacteria will remain so, but with long-term antibiotic therapy they will also learn to protect themselves from medicinal components, that is, they will gain additional benefits. At the same time, scientists discovered another interesting feature: bacteria from the walls of the cave, which was hidden from people for about 4 million years, were resistant to at least one modern antibiotic! Moreover, antibiotics are a product of the vital activity of microorganisms; bacteria have been using them for 2 billion years.

Not long ago it turned out that bacteria can destroy antibiotics and this feature is fixed at the genetic level, fixed in DNA - this is how superbugs are obtained. In addition, at the source of infection, bacteria are having their own “war” for territory. Some bacteria destroy others, picking up DNA residues that may contain a resistance gene. Does this mean we will all die from superbugs? No. We must not forget that we have an immune system, and scientists are also developing drugs that do not allow the resistance gene to attach to the transport components of bacteria - plasmids - it is the plasmids that are responsible for the transfer of genetic information.

Be sure to complete the course if an antibiotic is prescribed to treat a chronic infection or severe infections. In acute cases, when treating, for example, acute otitis media, if the condition significantly improves, consult a doctor to adjust your medication schedule; perhaps the doctor will stop the antibiotic, or perhaps not. Everything is individual.

Injections are better

No, injections are not better. Previously, the release of dosage forms that would retain the required bioavailability, storage properties and would not be destroyed in the stomach would be problematic, so doctors preferred injections, especially if the infectious process had gone too far. Today, even in hospitals they try to prescribe tablet forms whenever possible. Their bioavailability is practically not inferior to injectable forms, the only thing is that the tablets begin to act a little later. The exceptions are intravenous injections - the antibiotic acts almost instantly and drugs that are destroyed by enzymes. Injections are painful, stressful especially for children, there are the classic risks of infection, and there is also the risk of abscesses and other complications.

Do you take antibiotics for prevention?

Briefly: yes and no.

Taking a pack of pills to avoid getting sick after hypothermia is not prevention. The so-called preventive use of antibiotics is justified if there is a high risk of severe or dangerous infections. Thus, antibiotic prophylaxis is often prescribed in venereology and other areas of medicine. The norm is to take an antibiotic tablet before and after tooth extraction, installation of a dental implant, and during surgical interventions. Antibiotic prophylaxis is prescribed only by a doctor.

Antibiotics are evil for children and pregnant women

You can often find a pregnant woman who tries to treat infectious processes with home methods, believing that the medicine will harm the unborn child. You need to be aware of the risks first of all: the doctor, of course, tries to minimize the use of medications during this period, but pregnant women undergo operations, dental treatment, a lot of other procedures, and refusal of antibiotics where necessary can lead to infection of the fetus including. WHO regularly updates the list of drugs for pregnant women and children. There are recommended, controlled and spare ones. If you are worried, go to the WHO website - approved drugs are highlighted in green, prohibited drugs are in red, controlled and spare drugs are in yellow.

Without a sensitivity test, there is no point in taking antibiotics

In typical cases, conditions of moderate severity and for obvious reasons - some infectious processes have too typical a clinical picture, which is used as a diagnostic criterion; there is no practical sense in an antibiogram.

How an antibiogram is performed: the doctor takes material, for example, from a wound. In the laboratory, a microorganism is isolated that causes an infectious process (this takes at least 2-3 days), then a pure culture is isolated and, roughly speaking, confetti-sized disks are laid out, which are soaked in an antibiotic. Around the most effective ones there will be a maximum clean zone from bacterial colonies. On average, an antibiogram takes 3-7 days to prepare. Treatment ALWAYS begins immediately; during the course of treatment, the antibiotic may be changed, taking into account the antibiogram data. It is not done in all cases, but in the treatment of chronic infections, complex extensive infections. In typical cases, data show that the effectiveness of first-line antibiotics is not much lower than those selected using an antibiogram.

Do I need to take antibiotics for viral infections?

In short: sometimes you need it, sometimes you don’t.

Antibiotics do not act on viruses, but bacterial complications often develop against the background of viral infections. Often the doctor prescribes antibiotics because patients are waiting for appointments, although physical methods are almost always sufficient to treat acute respiratory viral infections, including influenza. Very rarely, an antibiotic for ARVI is prescribed prophylactically if the patient is weakened, has immunodeficiency, extremely low body weight (in children), or old age.

Antibiotics kill all living things and “burn out” the flora

In short: more likely no than yes.

Antibiotics do not kill any microbial cell; they act selectively, taking into account the biochemistry and characteristics of pathogenic agents - the drug either destroys the wall of the microbial cell, or stops reproduction, or acts on another target. The antibiotic only partially affects “its own” people, but already 3-5 days after the end of the course, and for the majority, after 1-2 days, the intestinal microflora is restored without additional intake of probiotics. There is an opinion that probiotics are useless: in case of serious violations of the flora, they do not help, and a conditionally healthy person recovers on his own after a course of antibiotics. Stories that someone once took a loading dose of an antibiotic and now has dysbiosis for life are fairy tales. But if you want to speed up the restoration of flora, drink kefir.

Antibiotics spoil the immune system and a healthy body is able to cope with infections on its own

Briefly: yes and no

Indeed, for some infections, the doctor does not prescribe an antibiotic. For example, for deep abrasions that have become inflamed, dressings and regular washing are enough, antibiotic therapy for bronchitis and pharyngitis is not always prescribed. But the body cannot cope with all infections on its own. Peritonitis, in general, occurs because you couldn’t handle it yourself. Antibiotics do not affect the immune system: the medicine works separately, and the immune cells work separately. Standard antibiotics do not affect the immune system, but there are antibiotics that are initially cytostatic, and they are called antitumor, and for a number of primary immunodeficiencies, antibacterial drugs are taken for several years.

Express replies:

Do antibiotics damage the liver? No. There are drugs that multiply the side effects of each other. Tell your doctor what medications you are taking so he can choose safe antibiotics.

How to drink it? Read the instructions or ask your doctor. Usually antibiotics are taken 1-2 hours after meals with water. You can’t use milk, kefir, jelly or anything else - the active substance is destroyed.

How to recycle? Expired medications should not be flushed down the drain - they have their own life there, which creates resistance to the drugs. Some cities have collection points for expired medications; if they are not available, pour the medications with sand or soil into a plastic container and dispose of them with household waste. This will reduce the risk of children or animals eating the pills.

Antibiotics should not be given to patients with allergies. Can. If an antibiotic provokes an attack, which most often ends at the level of urticaria and is stopped by a single dose of antihistamines, then another one is selected. Abscesses and purulent inflammations are much more dangerous than short-term urticaria. Modern drugs are synthetic and extremely rarely cause allergies; allergy symptoms often occur against the background of massive death of microorganisms.

Modern meat is laced with antibiotics and is dangerous . No. Antibiotics have always been used in animal husbandry; they in no way affect the human body. There are acceptable standards, farmers are obliged to comply with them.

Conclusion : the prescription of antibiotics must be justified, and the duration of the course is selected individually, taking into account the severity of the condition, danger and characteristics of the infectious process. When a doctor prescribes the same regimen for everyone, this is not entirely correct; drugs need to be selected individually - this concerns the dose, frequency of administration and other features. In our clinic you will find excellent specialists who select treatment in such a way as to cure you in the shortest possible time and without delayed risks to the body. We issue sick leave certificates, we have our own laboratory where you can test for sensitivity to antibiotics, including

Macrolides

This is a group of antibiotics created to suppress most pathogens of infectious diseases of the genitourinary system, including adnexitis. Maroclides include kacid, summed and other drugs. Such antibiotics have a long half-life and resistance to the acidic gastric environment.

Fluoroquinolones can confidently be called the most effective antibiotics that are used to treat inflammatory processes in the appendages. Infectious agents develop immunity to them very slowly. Most often, patients are prescribed: levofloxacin, gatifloxacin, norfloxacin, ofloxacin and other drugs of this group.

Is one antibiotic suitable for curing inflammation of the thyroid gland? In most cases, the answer will be negative, since inflammation is the result of the activity of several pathogens, and not just one. Some of them develop with access to air (aerobes), while others (anaerobes) develop without it.

To suppress the activity of all groups of pathogens, various types of antibacterial agents are prescribed. Tinidachol and metronidazole are especially effective in combating anaerobes in combination with antibiotics. If a chronic disease is suspected, material is often taken from women for research by biopsy (it may or may not be sterile). Chronic inflammation in many cases requires the use of effective antibiotics. Suppositories will also be effective for inflammation of the appendages.

You can make an appointment with a doctor by phone in Moscow: +7 (495) 601–15–15 or here. you can see the doctor here.

Principles for choosing antimicrobial drugs

Self-medication with antibiotics is strictly prohibited, since uncontrolled use of potent drugs can weaken the body and worsen the body's defense reactions. The drugs are selected exclusively by the doctor, taking into account the form of the disease and the patient’s condition.

Indications for prescribing antibiotics for the treatment of infectious diseases are the following:

  • Development of bacterial microflora in the respiratory tract. This is indicated by sputum with a green or yellow tint, which comes out with a cough.
  • Maintaining body temperature above 38.5°C for more than 4 days.
  • Severe weakness and the appearance of severe fatigue with minimal exertion.
  • The presence of purulent mucus in the stool.

Before a certain type of antibiotic is prescribed, a bacteriological culture must be carried out. To do this, take a swab from the nasopharynx and trachea, as well as mucus from the stool. Samples are placed in a nutrient medium to determine the type of microorganism. After this, a group of antibiotics is selected that destroy certain bacteria.

To ensure that the chosen antibiotic does not provoke a deterioration in the general condition, the following general tests are performed:

  • Blood. During the test, the number of main components is determined. When using antimicrobial drugs, a decrease in their levels may occur, so it is important to exclude the possibility of critical indicators.
  • Urine. Testing allows you to determine the condition of the urinary system and prevent possible inflammatory processes due to increased stress on the organs when removing the antibiotic from the body.

Also carried out:

  • Biochemical blood test to exclude exacerbations of existing pathologies when using potent antimicrobial drugs.
  • CT scan of the chest to assess the extent of damage to the lung tissue and select the dosage of the antibiotic.
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