Place of the drug Imudon in the pharmacotherapy of diseases of the maxillofacial area

As a result of the development of infectious and inflammatory diseases of the throat and oral cavity, an unpleasant and even cutting pain in the throat often appears. An unpleasant symptom negatively affects general well-being and interferes with normal eating, drinking and talking. The pain most often continues for several days. To alleviate the condition, many doctors advise taking Imudon.

Imudon is a medicine that is of bacterial origin. Has an immunostimulating effect. The drug helps to overcome the emerging disease. Before taking it, you should read the indications, instructions for use and make sure there are no contraindications.

Compatibility of Imudon and alcohol

? Imudon enters the body orally. But its main effect is not formed in the systemic bloodstream, but only in the oral cavity, nasopharynx, and saliva.

When drinking alcoholic beverages, intoxication occurs. It is accompanied by dizziness, nausea, and vomiting. If the tablet is eliminated along with vomit, there will be no effect.

If a person drinks alcohol during a period of pharyngitis, tonsillitis, or other acute or chronic diseases of an infectious nature, the condition worsens. Body temperature becomes higher due to vasodilation. The work of the kidneys, which actively secrete the active ingredient, is enhanced. It does not have time to get into the lesion, so the proliferation of viruses and bacteria progresses.

The product has a small list of side effects. But they appear or intensify if ethanol penetrates. Areas of rashes form on the skin and mucous membranes. If the infectious pathology affects the trachea and bronchi, a cough develops and the risk of bronchial asthma increases.

Due to severe fever, convulsions and neurological disorders may begin. Before using the medicine, consult a doctor for recommendations and contraindications.

List of analogues is cheaper

As a prevention of ENT diseases during pregnancy, Lizobact is a safe and cheap replacement for the original immunostimulant.

The price of Imudon in January 2021 is from 470 rubles. for 24 pcs., from 610 rub. for 40 tablets. If we consider a 10-day treatment course for adults, then you will need two packages of 40 tablets, which will amount to an average of 1,220 rubles.

Prevention will cost from 1830 rubles and will require 120 tablets. Patients often ask whether there are analogues of Imudon that are cheaper, but no less effective?

Imudon does not have exact structural analogues (generics), so if necessary, the doctor can offer a list of drugs that are similar in their action, from a similar pharmacological group, but with a different composition.

• Anaferon - from 210 rub. A homeopathic remedy that has a similar immunomodulatory and anti-inflammatory effect. Treatment begins with the appearance of the first symptoms of the disease. After improvement occurs, it is recommended to use the tablets for 1 week - 10 days. The medication is well tolerated by patients; in rare cases, allergic reactions have been reported.
• Derinat - from 290 rub. An inexpensive immunostimulant that activates cellular and humoral immunity. The drug is intended for local use, preparing a solution for rinsing the mouth, applying applications, and performing irrigations. The medicine is well tolerated by patients.

• Ribomunil - from 260 rub. A cheap analogue of Imudon based on bacterial ribosomes: the most common pathogens of infectious diseases affecting the upper respiratory tract and ENT organs.

At the beginning of treatment, nausea, vomiting, excessive salivation, stool disorders, and allergies may develop. This is normal and there is no need to stop the medication.

The drug is recommended to be used in the morning, on an empty stomach.

During the first 3 weeks, the medication is taken on the first 4 days of the week. In the next 5 months - in the first 4 days of each month.

The selection of similar drugs and substitutes should be trusted to a qualified doctor. Self-medication is unacceptable, as it may not provide the desired therapeutic result.

Brief characteristics of the drug

Imudon consists of lysates of various types of bacteria. Due to them, an immunostimulating effect is formed.

Despite the presence of microorganisms of bacterial origin, a beneficial effect is formed:

• gradual colonization of the mucous membrane of the nasopharynx by microflora, which leads to the adaptation of the immune system and the absence of a sharp inflammatory reaction;
• increased phagocytosis and activity of leukocytes;
• production of interferon, lysozyme, immunoglobulin A.

All reactions occur in saliva; no systemic changes occur. Therefore, the active components are well tolerated by the body. The instructions for use include the following indications:

• pharyngitis, tonsillitis;
• preparation for tonsillectomy, that is, surgical removal of the tonsils;
• periodontal disease, periodontitis – constant inflammation of the gums;
• stomatitis, glossitis, gingivitis - an inflammatory condition of the gums, tongue, periodontal junction of an infectious nature;
• violation of the ratio of oral microflora;
• prevention and treatment of infection after tooth extraction or implantation of artificial elements, dentures;
• development of ulcers.

The product is taken orally, dissolving in the mouth. The dosage is individual, depending on the age and degree of development of the disease.

Possible negative influences:

• local allergies to the skin or mucous membranes - itching, burning, rash, irritation, swelling, redness;
• systemic hypersensitivity – angioedema, anaphylactic shock, urticaria;
• spasm of areas of the bronchial tree;
• hemorrhagic vasculitis, erythema, thrombocytopenia.

The substance is contraindicated for children under 3 years of age, during pregnancy and lactation, and in case of individual intolerance.

pharmachologic effect

The drug helps provide an immunostimulating effect similar to a vaccine. The effect of Imudon is due to its ability to stimulate the process of capture and digestion of solid particles that are part of pathogenic microorganisms.

Under the influence of the drug, the quantitative content of lysozyme, interferon, and immunoglobulins— the main immune cells of the body—increases.

The tablets consist of a polyvalent antigenic complex - a mixture of bacteria and products of their breakdown into individual enzymes, which include elements of the cell walls and intracellular contents of the microorganism.

The medicine has a composition similar to the causative agents of those pathological processes that are most often observed in the mouth and pharynx, due to which the body begins to intensify the production of its own protective bodies against specific types of bacteria.

Use of the drug for alcoholism

Alcoholism causes severe, chronic pathologies. Among them are hepatitis, fibrosis, liver cirrhosis, colitis (intestinal damage), encephalopathy, hyperbilirubinemia.

Damage leads to deterioration in absorption and metabolism of the drug. The patient consumes it, but immunization does not occur. The bacilli are not destroyed without affecting the lesion.

In an alcoholic, infectious and inflammatory pathology of the pharynx and oral cavity progresses. It is dangerous due to the lack of penetration of the active component into the systemic bloodstream due to excessive vasodilation under the influence of alcohol.

There is a risk of developing the following deviations:

• pericarditis – infection of the pericardial sac;
• pyelonephritis - inflammation of the kidneys of a bacterial nature;
• sepsis is blood poisoning.

Doctors explain that if there is an addiction, it is difficult or impossible to cure a chronic pathology. A complete waiver is required.

When is it indicated to take Imudon during pregnancy?

Imudon is prescribed for the treatment of bacterial diseases of a dental and otolaryngological nature:

• glossitis;
• pharyngitis;
• periodontal disease;
• oral dysbiosis;
• periodontitis;
• all forms of stomatitis;
• tonsillectomy;
• unpleasant odor from the mouth;
• gingivitis of various etiologies;
• infection of the nasopharynx;
• tonsillitis in any form.

On a note! In dentistry, Imudon is often used to prevent infectious complications after tooth extraction or as a result of injuries from dentures.

Consequences of drinking alcohol

If the patient violates the ban on simultaneous use, the following consequences arise:

• progression of the disease, proliferation of pathogenic flora, which begins to spread to neighboring tissues;
• risk of tracheitis, bronchitis, pneumonia;
• excessive activity of the immune system, it simultaneously fights ethanol and bacteria, which leads to rashes, swelling of the mucous membranes, and changes in blood composition;
• decrease in platelet count.

Alcohol and microorganisms do not cross-react. There are no consequences for the digestive tract, liver, or urinary system.

Organs affected by the toxin

The combined use of pharmacological agents and alcohol has a toxic effect on the internal organs and environments of the body. Alcohol, entering into a chemical reaction with a medicine, leads to poisoning, disrupts physiological processes, enhances or weakens the healing properties of drugs.

The liver suffers more than other organs. She gets hit twice. Many medications have a side effect - hepatotoxicity, destroy cells, and disrupt the physiology of the organ. In the liver, alcohol breaks down to ethanal, a substance 20-30 times more toxic than ethanol, which causes the death of hepatocytes.

Dangerous groups of drugs for the organ in combination with alcohol:

• anti-inflammatory;
• hormonal;
• antibacterial;
• antifungal;
• glucose control agents for diabetes mellitus;
• anti-tuberculosis;
• cytostatics (chemotherapy drugs);
• tranquilizers (anti-epileptic, psychotropic).

In second place among the internal organs exposed to the harmful effects of alcohol together with medications are the heart and vascular system. Strong drinks during drug therapy constrict blood vessels and increase blood pressure. The simultaneous intake of alcohol and chemical substances leads to failure of the myocardium and increases the risk of developing an attack of angina pectoris and a heart attack.

A mixture of ethanol and pharmaceuticals disrupts the quality of the blood and reduces clotting. This is dangerous due to internal bleeding and strokes.

Rules for taking medications and alcohol

Drinking alcohol during treatment minimizes the clinical effect of therapy and creates a risk of developing complications of the disease.

If this cannot be avoided, follow the rules of behavior that will reduce the occurrence of negative consequences:

1. Do not drink strong drinks (vodka, cognac, whiskey), choose dry wine (100-150 ml), beer (no more than 300 ml). Don't drink alcohol on an empty stomach.
2. The interval between taking the medicine and alcohol should be at least 2 hours.
3. To reduce the toxic effect, take medications that protect the liver (hepatoprotectors), pancreas (pancreatin), and stomach (antacids ─ Rennie, Almagel).

If a person takes antiviral medications for colds, anti-inflammatory drugs, alcohol in moderation does not pose a threat to the body.

Alcoholic drinks during treatment are strictly contraindicated in cases of liver cirrhosis, severe infectious diseases, and during a course of chemotherapy.

special instructions

Children under 6 years of age should take the tablets only under parental supervision.

If the patient needs to rinse the mouth, this can be done at least an hour after taking the tablet, otherwise its therapeutic effect will be reduced.

Taking the medicine does not in any way affect the ability to drive vehicles and other mechanisms that require special concentration.

If a person has bronchial asthma, then using the drug can aggravate the condition and lead to another attack, so in this case, taking Imudon is contraindicated.

Medicines, alcohol and chronic diseases

If a person has chronic diseases, simultaneous use of alcohol and medications is potentially dangerous for the functioning of vital organs. Since patients systematically take prescribed medications, the influence of alcohol can lead to negative consequences.

People with chronic heart disease (angina pectoris, heart defects) develop arrhythmias of varying severity. Heart attacks with severe pain syndrome develop, which is not relieved by Nitroglycerin, and the risk of developing myocardial infarction increases significantly.

In case of chronic liver diseases (viral hepatitis, hepatosis), alcohol during treatment can become a trigger in the development of cirrhosis and hepatocellular carcinoma (cancer).

Drinking alcohol during cirrhosis leads to the following consequences:

• bleeding into the abdominal cavity;
• liver decomposition, infection, peritonitis;
• hepatic coma;
• death.

If a person is on long-term treatment with sedatives, psychotropic drugs, tranquilizers, he is contraindicated in drinking alcohol. This leads to severe depression and the appearance of obsessive states (hallucinations, phobias). Suicidal feelings develop. Such a patient needs constant monitoring and assistance from a psychiatrist.

The most dangerous combinations and consequences

The combination of alcohol and chemical-based drugs can lead to serious disorders in the body, and in some cases to fatal consequences.

List of medications and their side effects in combination with alcohol: